Orthopedic Hospital of Oklahoma

Peripheral Neuropathy

Peripheral neuropathy is an inflammation and/or degeneration of the nerves in the extremities.  Although it is not known what actually causes the condition to develop, it often occurs in people with diabetes, alcoholism, certain immune system disorders, and in people who have deficiencies in vitamin B12, thiamine, and folic acid.

The symptoms of Peripheral Neuropathy primarily occur in the hands and/or feet and include a burning pain or numbness and tingling. Any pressure to the hand and feet causes pain, sometimes even to the point of not being able to tolerate socks on your feet or being able to pick up items with your fingers. Walking can be difficult and your balance may be poor. You may experience clumsiness in the hands.

There is no cure for neuropathy. Treatment focuses instead on the symptoms and includes:

  • Adequate pain management- many different types of pain medications may be tried before an effective medication at the appropriate dose is found
  • Anti-depressant medications have been used successfully
  • Topical creams
  • Immunoglobulin (special type of antibody)injections
  • Plasmapheresis treatments involve removing some of the patient’s blood and transfusing certain blood products back into the patient